Articles Tagged With:
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Driving Pressures More Strongly Predicted Survival than P/F Ratios in Patients with ARDS
Optimizing positive end-expiratory pressure to minimize driving pressure may be a better strategy for ventilator adjustment than maximizing partial pressure of arterial oxygen/fraction of inspired oxygen (P/F) ratios to improve outcomes in patients with acute respiratory distress syndrome. -
Elucidating the Long-Term Effects of COVID-19
In this prospective uncontrolled cohort study of COVID-19 survivors performed four months after their hospitalization, many patients reported at least one symptom not previously present, and abnormalities on lung computed tomography scan were common. -
High Pleural Pressure Prevents Overdistension in ARDS Patients with High Body Mass Index
High airway pressure is required to recruit lung atelectasis in patients with acute respiratory distress syndrome and body mass index ≥ 35 kg/m2. -
Use Push-Dose Phenylephrine with Caution in Septic Patients
Phenylephrine pushes in septic patients were associated with early hemodynamic stability, but higher intensive care unit mortality.
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Texas Judge Tosses Suit Over COVID-19 Vaccine Mandate
Plaintiffs expected to challenge ruling in ongoing saga over Houston facility’s policy. -
Truth in Healthcare Advertising: What's In a Name?
Controversy emerges over recent change from “physician assistant” to “physician associate.” -
Evaluation of an Inpatient Postpartum Human Papillomavirus Immunization Program
In this cohort study, results from two years of an inpatient postpartum HPV vaccination program are presented. Overall, their results show an increased rate of immunization (hazard ratio of 2.51) and an increased proportion of women completing the vaccination series (35.8% of those receiving an inpatient dose completed the series compared to 9.3% of those who did not get the inpatient dose).
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When Is the Ideal Time in the Menstrual Cycle for IUD Insertion?
In this retrospective cohort study, women using the levonorgestrel intrauterine device for noncontraceptive indications had higher expulsion rates (38% vs. 17%, P = 0.03) when insertion occurred on day 1 to day 8 of the menstrual cycle compared to after day 8.
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The Association Between SSRIs and Congenital Anomalies
In this synthesis involving 15 meta-analytic studies, four studies demonstrated an association between paroxetine use during pregnancy and increased risk of major congenital anomalies (relative risk [RR], 1.18 [95% confidence interval (CI), 1.05, 1.32] to 1.29 [95% CI, 1.11-1.49]). For all selective serotonin reuptake inhibitors (SSRIs), the RR for major anomalies (1.10 [95% CI, 1.03, 1.16] to 1.27 [95% CI, 1.09, 1.47]) and cardiac defects (1.06 [95% CI, 0.94, 1.18] to 1.36 [95% CI, 0.61, 3.04]) were increased. This meta-analysis suggests an increased risk of cardiac and major anomalies with SSRI use, but the results should be interpreted with caution, since all included studies were meta-analyses of retrospective cohort studies.
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Management of Heavy Menstrual Bleeding: Levonorgestrel-Releasing Intrauterine System vs. Endometrial Ablation
In this multicenter, randomized, noninferiority trial among patients aged 34 years and older with heavy menstrual bleeding, the levonorgestrel-releasing intrauterine system did not meet the noninferiority threshold when compared to endometrial ablation for mean blood loss at 24 months following intervention. Both interventions did lead to large decreases in blood loss and comparable satisfaction and quality-of-life scores.